TargetMol

Meclofenamic acid

Product Code:
 
TAR-T11990
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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This product comes from: United States.
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Further Information

Bioactivity:
Meclofenamic acid is a non-selective gap-junction blocker and a selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic acid has anti-inflammatory activities.
CAS:
644-62-2
Formula:
C14H11Cl2NO2
Molecular Weight:
296.15
Pathway:
Cytoskeletal Signaling;
Purity:
0.98
SMILES:
Cc1ccc(Cl)c(Nc2ccccc2C(O)=O)c1Cl
Target:
Gap Junction Protein

References

1. Conroy MC, et al. Pharmacology, pharmacokinetics, and therapeutic use of meclofenamate sodium. Clin J Pain. 1991;7 Suppl 1:S44-8. 1. Eleftheriou CG, et al. Meclofenamic acid improves the signal to noise ratio for visual responses produced by ectopicexpression of human rod opsin. Mol Vis. 2017 Jun 16;23:334-345. eCollection 2017. 3. Huang Y, et al. Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5. Nucleic Acids Res. 2015 Jan;43(1):373-84.