TargetMol

Kira8 Hydrochloride

Product Code:
 
TAR-T11762
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11762-5mg5mg£930.00
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TAR-T11762-50mg50mg£1,821.00
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Quantity:
TAR-T11762-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
CAS:
2250019-92-0
Formula:
C31H30Cl2N6O3S
Molecular Weight:
637.58
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.98
SMILES:
Cl.Cc1ccc2c(NS(=O)(=O)c3ccccc3Cl)cccc2c1Oc1ncccc1-c1ccnc(N[C@@H]2CCCNC2)n1
Target:
Adenosine Receptor

References

1. Morita S, et al. Targeting ABL-IRE1? Signaling Spares ER-Stressed Pancreatic ? Cells to Reverse Autoimmune Diabetes. Cell Metab. 2017 Apr 4;25(4):883-897.e8.