TargetMol

KDM4-IN-2

Product Code:
 
TAR-T11749
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11749-5mg5mg£617.00
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TAR-T11749-50mg50mg£1,661.00
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Quantity:
TAR-T11749-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
KDM4-IN-2 is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 nM for KDM4A and KDM5B, respectively.
CAS:
2369607-62-3
Formula:
C25H26N6O
Molecular Weight:
426.524
Pathway:
Metabolism
Purity:
0.98
SMILES:
O=c1[nH]cnc2c(nccc12)-n1cc(CCN2CCC3(CCc4ccccc34)CC2)cn1
Target:
Glucokinase

References

1. Le Bihan YV, et al. C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays. Eur J Med Chem. 2019 Sep 1;177:316-337.