TargetMol

Haemanthamine

Product Code:
 
TAR-T11534
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T11534-5mg5mg£766.00
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Further Information

Bioactivity:
Haemanthamine is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiviral, antioxidant, and anticonvulsant activities.
CAS:
466-75-1
Formula:
C17H19NO4
Molecular Weight:
301.342
Purity:
0.98
SMILES:
[H][C@]12C[C@H](OC)C=C[C@@]11[C@@H](O)CN2Cc2cc3OCOc3cc12

References

1. Pellegrino S, et al. The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth. Structure. 2018 Mar 6;26(3):416-425.e4. 2. Seifrtov? M, et al. Haemanthamine alters sodium butyrate-induced histone acetylation, p21WAF1/Cip1 expression, Chk1 and Chk2 activation and leads to increased growth inhibition and death in A2780 ovarian cancer cells. Phytomedicine. 2017 Nov 15;35:1-10.