TargetMol

DS88790512

Product Code:
 
TAR-T11105
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11105-5mg5mg£1,572.00
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TAR-T11105-50mg50mg£3,107.00
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TAR-T11105-100mg100mg£4,247.00
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This product comes from: United States.
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Further Information

Bioactivity:
DS88790512, IC50 at 11 nM, is an effective, selective, oral bioeffective TRPC6 inhibitor.
CAS:
2231089-95-3
Formula:
C22H29N3O2
Molecular Weight:
367.493
Purity:
0.98
SMILES:
[H][C@]12C[C@H]([C@H](Oc3ccc(cc3)C#N)[C@@]1(C)CCC(=O)C2)N1CCC[C@@H](N)C1

References

1. Motoyama K, et al. Discovery of a bicyclo[4.3.0]nonane derivative DS88790512 as a potent, selective, and orally bioavailable blocker of transient receptor potential canonical 6 (TRPC6). Bioorg Med Chem Lett. 2018 Jul 1;28(12):2222-2227.