TargetMol

Cirsiliol

Product Code:
 
TAR-T10821
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Cirsiliol is a selective inhibitor of 5-lipoxygenase and a competitive low-affinity ligand of benzodiazepine receptors.
CAS:
34334-69-5
Formula:
C17H14O7
Molecular Weight:
330.292
Pathway:
Metabolism
Purity:
0.98
SMILES:
COc1cc2oc(cc(=O)c2c(O)c1OC)-c1ccc(O)c(O)c1
Target:
Lipoxygenase

References

1. Mustafa EH, et al. Effects of cirsiliol, a flavone isolated from Achillea fragrantissima, on rat isolated ileum. Gen Pharmacol. 1992 May;23(3):555-60. 2. Kang J, et al. Rhamnetin and cirsiliol induce radiosensitization and inhibition of epithelial-mesenchymal transition (EMT) by miR-34a-mediated suppression of Notch-1 expression in non-small cell lung cancer cell lines. J Biol Chem. 2013 Sep 20;288(38):27343-57.