TargetMol

BMVC

Product Code:
 
TAR-T10574
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10574-5mg5mg£270.00
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TAR-T10574-50mg50mg£1,026.00
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Quantity:
TAR-T10574-100mg100mg£1,564.00
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This product comes from: United States.
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Further Information

Bioactivity:
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities. BMVC inhibits Taq DNA polymerase (IC50: ~2.5 μM).
CAS:
627810-06-4
Formula:
C28H25I2N3
Molecular Weight:
657.338
Pathway:
DNA Damage/DNA Repair
Purity:
0.98
SMILES:
[I-].[I-].C[n+]1ccc(C=Cc2ccc3[nH]c4ccc(C=Cc5cc[n+](C)cc5)cc4c3c2)cc1
Target:
Telomerase

References

1. Huang FC, et al. G-quadruplex stabilizer 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide induces accelerated senescence and inhibits tumorigenic properties in cancer cells. Mol Cancer Res. 2008 Jun;6(6):955-64. 2. Jen-Fei Chu, et al. A Novel Method for Screening G-quadruplex Stabilizers to Human Telomeres. Journal of the Chinese Chemical Society, 2011, 58, 296-300.