TargetMol

BMT-124110

Product Code:
 
TAR-T10572
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10572-1mg1mg£335.00
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TAR-T10572-5mg5mg£711.00
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TAR-T10572-1mL1 mL * 10 mM (in DMSO)£836.00
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TAR-T10572-10mg10mg£946.00
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TAR-T10572-25mg25mg£1,396.00
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TAR-T10572-50mg50mg£1,862.00
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Further Information

Bioactivity:
BMT-124110 is an effectivet, selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE; IC50: 17 nM) and Cyclin G-associated kinase (GAK; IC50: 99 nM).
CAS:
1679371-59-5
Formula:
C21H27N3O3
Molecular Weight:
369.465
Pathway:
Neuroscience
Purity:
0.98
SMILES:
CC(C)C[C@](C)(N)COc1ccc-2c(OCc3cnc(NC(C)=O)cc-23)c1
Target:
AAK1 (AP2 associated kinase 1)

References

1. Kostich W, et al. Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86.