TargetMol

YM158 free base

Product Code:
 
TAR-T10501
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T10501-5mg5mgEnquire
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Further Information

Bioactivity:
YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87).
CAS:
179102-65-9
Formula:
C32H33ClN6O5S2
Molecular Weight:
681.22
Purity:
0.98
SMILES:
CC(C)(C)c1csc(COc2cccc(c2)C(=O)Nc2cc(CCCS(=O)(=O)c3ccc(Cl)cc3)ccc2OCc2nnn[nH]2)n1

References

1. Arakida Y, et al. In vitro pharmacologic profile of YM158, a new dual antagonist for LTD 2. Arakida Y, et al. Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs. J Pharmacol Exp Ther. 1999 Sep;290(3):1285-91.