TargetMol

BCR-ABL-IN-1

Product Code:
 
TAR-T10488
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10488-5mg5mg£850.00
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Quantity:
TAR-T10488-50mg50mg£1,661.00
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Quantity:
TAR-T10488-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.
CAS:
188260-50-6
Formula:
C23H21F4N5O
Molecular Weight:
459.449
Pathway:
Cytoskeletal Signaling; Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.98
SMILES:
NCCCn1ccc2c(cccc12)-c1ccnc(Nc2cccc(OC(F)(F)C(F)F)c2)n1
Target:
Bcr-Abl

References

1. Cui J1, et al. BCR-ABL tyrosine kinase inhibitor pharmacophore model derived from a series of phenylaminopyrimidine-based (PAP) derivatives. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2442-50.