TargetMol

BACE1-IN-2

Product Code:
 
TAR-T10451
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10451-5mg5mg£1,412.00
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Quantity:
TAR-T10451-50mg50mg£2,785.00
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Quantity:
TAR-T10451-100mg100mg£3,765.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).
CAS:
1352416-78-4
Formula:
C19H15F4N5O2
Molecular Weight:
421.356
Pathway:
Neuroscience
Purity:
0.98
SMILES:
C[C@@]1(N=C(N)CO[C@H]1C(F)(F)F)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F
Target:
BACE

References

1. Gijsen HJM, et al. Optimization of 1,4-Oxazine ?-Secretase 1 (BACE1) Inhibitors Toward a Clinical Candidate. J Med Chem. 2018 Jun 28;61(12):5292-5303.