TargetMol

AZD-5991 Racemate

Product Code:
 
TAR-T10434L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10434L-5mg5mg£850.00
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Further Information

Bioactivity:
AZD-5991 Racemate is the racemate of AZD-5991. AZD-5991 Racemate is an Mcl-1 inhibitor (IC50: <3 nM in FRET assay).
CAS:
2143010-83-5
Formula:
C35H34ClN5O3S2
Molecular Weight:
672.26
Pathway:
Apoptosis
Purity:
0.98
SMILES:
O=C(O)C1=C(CCCOC2=C(C=CC=C3)C3=CC4=C2)C5=C(N1C)C(C6=C(C)N(C)N=C6CSCC7=NN(C)C(CS4)=C7)=C(Cl)C=C5
Target:
BCL

References

1. Tron AE, et al. Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nat Commun. 2018 Dec 17;9(1):5341.