TargetMol

ASP1126

Product Code:
 
TAR-T10387
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10387-5mg5mg£930.00
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TAR-T10387-50mg50mg£1,821.00
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Quantity:
TAR-T10387-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist (EC50s: 7.12 nM, 517 nM for hS1P1 and hS1P3).
CAS:
1228580-11-7
Formula:
C26H26ClF6NO5
Molecular Weight:
581.94
Purity:
0.98
SMILES:
Cl.OC(=O)C1CCN(CC2=Cc3ccc(OCc4ccc(OCC(F)(F)F)c(c4)C(F)(F)F)cc3OC2)CC1

References

1. Okimoto A, et al. ASP1126, a Novel Sphingosine-1-Phosphate-Selective Agonist With a Favorable Safety Profile, Prolongs Allograft Survival in Rats and Nonhuman Primates in Combination With Tacrolimus With a Broad Safety Margin for Bradycardia. Transplant Proc. 2019 Jul - Aug;51(6):2081-2098.