TargetMol

Antitrypanosomal agent 1

Product Code:
 
TAR-T10339
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10339-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T10339-100mg100mg£133.00
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Further Information

Bioactivity:
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).
CAS:
75144-12-6
Formula:
C11H14Cl3NO
Molecular Weight:
282.59
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
Cl.CN(C)CCC(=O)c1ccc(Cl)c(Cl)c1
Target:
Parasite

References

1. Martyn DC, et al. High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1280-3.