TargetMol

AMPA receptor modulator-1

Product Code:
 
TAR-T10307
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10307-1mg1mg£227.00
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TAR-T10307-5mg5mg£430.00
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TAR-T10307-1mL1 mL * 10 mM (in DMSO)£434.00
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TAR-T10307-10mg10mg£599.00
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TAR-T10307-25mg25mg£863.00
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TAR-T10307-50mg50mg£1,179.00
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Quantity:
TAR-T10307-100mg100mg£1,589.00
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Further Information

Bioactivity:
AMPA receptor modulator-1 is an orally active, and selective AMPAR regulatory protein TARP γ-8 negative modulator (pIC50: 9.7), more selective over GluA1/γ-2 (pIC50=5).
CAS:
2036074-41-4
Formula:
C16H11ClF3NO2
Molecular Weight:
341.71
Pathway:
Neuroscience|Membrane transporter/Ion channel
Purity:
0.98
SMILES:
Cc1cc(cc2CC(=O)Nc12)-c1c(Cl)cccc1OC(F)(F)F
Target:
iGluR

References

1. Ravula S, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP ?-8. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826.