TargetMol

KR-33493

Product Code:
 
TAR-TQ0220
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0220-1mg1mg£98.00
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TAR-TQ0220-5mg5mg£135.00
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TAR-TQ0220-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-TQ0220-10mg10mg£168.00
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TAR-TQ0220-25mg25mg£230.00
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TAR-TQ0220-50mg50mg£369.00
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Quantity:
TAR-TQ0220-100mg100mg£535.00
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Further Information

Bioactivity:
KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.
CAS:
1021497-97-1
Formula:
C20H18BrN3O3S
Molecular Weight:
460.35
Pathway:
Apoptosis
Purity:
0.98
SMILES:
OC(=O)c1nn(CCc2ccccc2)cc1NC(=O)CSc1ccc(Br)cc1
Target:
Fas/FasL

References

Jeong JW, et al. Subacute toxicity evaluation of KR-33493, FAF1 inhibitor for a new anti-parkinson's disease agent, after oral administration in rats and dogs. Regul Toxicol Pharmacol. 2016 Nov;81:387-396. Zhao F, et al. [Danggui Niantong decoction induces apoptosis by activating Fas/caspase-8 pathway in rheumatoid arthritis fibroblast-like synoviocytes]. Nan Fang Yi Ke Da Xue Xue Bao. 2020 Aug 30;40(8):1119-1126. Chinese.