TargetMol

d[Leu4,Lys8]-VP acetate

Product Code:
 
TAR-TP1927L1
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TP1927L1-1mg1mg£102.00
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TAR-TP1927L1-2mg2mg£114.00
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TAR-TP1927L1-5mg5mg£132.00
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TAR-TP1927L1-10mg10mg£168.00
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TAR-TP1927L1-25mg25mg£246.00
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TAR-TP1927L1-50mg50mg£335.00
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TAR-TP1927L1-100mg100mg£468.00
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Further Information

Bioactivity:
d[Leu4,Lys8]-VP acetate is a selective vasopressin V1b receptor agonist. The Kis for rat, human and mouse V1b receptors are 0.16 nM, 0.52 nM and 0.1.38 nM, respectively. d[Leu4,Lys8]-VP acetate exhibits weak antidiuretic, vasopressor and oxytocic activiti
CAS:
TP1927L1
Formula:
C49H71N11O13S2
Molecular Weight:
1086.28
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
CC(O)=O.NC(CNC([C@@H](NC([C@@H]1CCCN1C([C@@H](NC([C@@H]2CC(N)=O)=O)CSSCCC(N[C@H](C(N[C@](CC3=CC=CC=C3)([H])C(N[C@@H](CC(C)C)C(N2)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)CCCCN)=O)=O
Target:
Vasopressin Receptor

References

Ana P, et, al. Design and synthesis of the first selective agonists for the rat vasopressin V(1b) receptor: based on modifications of deamino-[Cys1]arginine vasopressin at positions 4 and 8. J Med Chem. 2007 Feb 22; 50(4): 835-47. Ana P, et, al. Pharmacological and physiological characterization of d[Leu4, Lys8]vasopressin, the first V1b-selective agonist for rat vasopressin/oxytocin receptors. Endocrinology. 2007 Sep; 148(9): 4136-46.