TargetMol

MNK8?

Product Code:
 
TAR-T9945
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9945-1mg1mg£124.00
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TAR-T9945-2mg2mg£147.00
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TAR-T9945-5mg5mg£181.00
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TAR-T9945-1mL1 mL * 10 mM (in DMSO)£185.00
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TAR-T9945-10mg10mg£227.00
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TAR-T9945-25mg25mg£349.00
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Quantity:
TAR-T9945-50mg50mg£470.00
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TAR-T9945-100mg100mg£651.00
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Quantity:
TAR-T9945-500mg500mg£1,291.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
3-methyl-6- (naphthalen-1-yl)pyrimidine-2,4(1H, 3H)-dione is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1].
CAS:
2055078-49-2
Formula:
C15H12N2O2
Molecular Weight:
252.27
Pathway:
Stem Cells; JAK/STAT signaling
Purity:
0.98
SMILES:
CN(C(C=C(c1cccc2ccccc12)N1)=O)C1=O
Target:
STAT

References

Ayyiliath M Sajith, et al. Pyrimidine-2,4-dione targets STAT3 signaling pathway to induce cytotoxicity in hepatocellular carcinoma cells. Bioorg Med Chem Lett. 2021 Oct 15;50:128332.