TargetMol

NSC 617145

Product Code:
 
TAR-T9168
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9168-1mg1mg£95.00
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Quantity:
TAR-T9168-2mg2mg£106.00
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TAR-T9168-5mg5mg£127.00
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TAR-T9168-1mL1 mL * 10 mM (in DMSO)£132.00
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TAR-T9168-10mg10mg£148.00
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Quantity:
TAR-T9168-25mg25mg£212.00
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Quantity:
TAR-T9168-50mg50mg£274.00
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TAR-T9168-100mg100mg£389.00
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Quantity:
TAR-T9168-500mg500mg£822.00
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Further Information

Bioactivity:
NSC617145 is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.
CAS:
203115-63-3
Formula:
C13H10Cl4N2O4
Molecular Weight:
400.03
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint
Purity:
0.9831
SMILES:
CC(C)(CN1C(=O)C(Cl)=C(Cl)C1=O)CN1C(=O)C(Cl)=C(Cl)C1=O
Target:
DNA/RNA Synthesis

References

Aggarwal, M., Banerjee, T., Sommers, J.A., et al. Werner syndrome helicase has a critical role in DNA damage responses in the absence of a functional fanconi anemia pathway. Cancer Res. 73(17), 5497-5507 (2013).