TargetMol

N-[5-[(4-Bromophenyl)methylene]-4,5-dihydro-4-oxo-2-thiazolyl]-1-naphthalenesulfonamide

Product Code:
 
TAR-T9063
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T9063-1mg1mg£113.00
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TAR-T9063-2mg2mg£131.00
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TAR-T9063-5mg5mg£148.00
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TAR-T9063-1mL1 mL * 10 mM (in DMSO)£181.00
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TAR-T9063-10mg10mg£193.00
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TAR-T9063-25mg25mg£289.00
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TAR-T9063-50mg50mg£389.00
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TAR-T9063-100mg100mg£544.00
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TAR-T9063-500mg500mg£1,099.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Pitstop 2 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research.
CAS:
1332879-52-3
Formula:
C20H13BrN2O3S2
Molecular Weight:
473.36
Pathway:
Microbiology/Virology; Proteases/Proteasome
Purity:
0.9991
SMILES:
O=C1N=C(S/C1=C/C2=CC=C(C=C2)Br)NS(=O)(C3=CC=CC4=C3C=CC=C4)=O
Target:
HIV Protease

References

Smith CM, et, al. Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells. Mol Cancer. 2013 Jan 17; 12:4. Kumar GA, et, al. Leishmania donovani Internalizes into Host Cells via Caveolin-mediated Endocytosis. Sci Rep. 2019 Sep 2; 9(1): 12636.