TargetMol

Oncrasin-1

Product Code:
 
TAR-T8006
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8006-2mg2mg£103.00
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TAR-T8006-5mg5mg£124.00
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TAR-T8006-10mg10mg£155.00
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TAR-T8006-1mL1 mL * 10 mM (in DMSO)£164.00
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TAR-T8006-25mg25mg£254.00
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TAR-T8006-50mg50mg£404.00
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TAR-T8006-100mg100mg£556.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations
CAS:
75629-57-1
Formula:
C16H12ClNO
Molecular Weight:
269.73
Pathway:
MAPK; GPCR/G Protein; Apoptosis
Purity:
0.9968
SMILES:
Clc1ccc(Cn2cc(C=O)c3ccccc23)cc1
Target:
Apoptosis; Raf; Ras

References

Guo W , Wu S , Liu J , et al. Identification of a Small Molecule with Synthetic Lethality for K-Ras and Protein Kinase C Iota[J]. Cancer Research, 2008, 68(18):7403-7408. Guo W , Wu S , Wang L , et al. Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1)[J]. Molecular Cancer Therapeutics, 2009, 8(2):441-448.