TargetMol

YM976

Product Code:
 
TAR-T7954
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7954-50mg50mgEnquire
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TAR-T7954-5mg5mg£105.00
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TAR-T7954-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T7954-10mg10mg£127.00
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TAR-T7954-25mg25mg£164.00
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This product comes from: United States.
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Further Information

Bioactivity:
YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)
CAS:
191219-80-4
Formula:
C17H16ClN3O
Molecular Weight:
313.79
Pathway:
Metabolism
Purity:
0.9984
SMILES:
CCc1ccc2c(nc(=O)n(CC)c2n1)-c1cccc(Cl)c1
Target:
PDE

References

Aoki M , Yamamoto S , Kobayashi M , et al. Antiasthmatic effect of YM976, a novel PDE4 inhibitor, in guinea pigs[J]. Journal of Pharmacology and Experimental Therapeutics, 2001, 297(1):165-173. Aoki M , Kobayashi M , Ishikawa J , et al. A Novel Phosphodiesterase Type 4 Inhibitor, YM976 (4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one), with Little Emetogenic Activity[J]. Journal of Pharmacology & Experimental Therapeutics, 2000, 295(1):255-260.