TargetMol

Thiorphan

Product Code:
 
TAR-T7693
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7693-1mg1mg£105.00
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TAR-T7693-2mg2mg£118.00
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TAR-T7693-5mg5mg£139.00
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TAR-T7693-1mL1 mL * 10 mM (in DMSO)£144.00
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TAR-T7693-10mg10mg£188.00
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TAR-T7693-25mg25mg£258.00
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TAR-T7693-50mg50mg£351.00
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TAR-T7693-100mg100mg£491.00
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Quantity:
TAR-T7693-500mg500mg£1,010.00
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Further Information

Bioactivity:
Thiorphan is an neprilysin inhibitor (NEP; IC50 : 0.007 μM).
CAS:
76721-89-6
Formula:
C12H15NO3S
Molecular Weight:
253.32
Pathway:
Metabolism
Purity:
0.9991
SMILES:
OC(=O)CNC(=O)C(CS)Cc1ccccc1
Target:
Neprilysin

References

Chicau-Chovet M , Dubrasquet M , Chariot J , et al. Thiorphan and acetorphan inhibit gastric secretion by a central, non-opioid mechanism in the rat[J]. European Journal of Pharmacology, 1988, 154(3):0-254. Mouri A , Zou L B , Iwata N , et al. Inhibition of neprilysin by thiorphan (i.c.v.) causes an accumulation of amyloid ? and impairment of learning and memory[J]. Behavioural Brain Research, 2006, 168(1):0-91.