TargetMol

Dihexa

Product Code:
 
TAR-T7376
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7376-1mg1mg£121.00
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TAR-T7376-2mg2mg£143.00
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TAR-T7376-5mg5mg£179.00
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TAR-T7376-10mg10mg£254.00
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TAR-T7376-1mL1 mL * 10 mM (in DMSO)£258.00
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TAR-T7376-25mg25mg£452.00
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TAR-T7376-50mg50mg£629.00
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TAR-T7376-100mg100mg£864.00
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This product comes from: United States.
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Further Information

Bioactivity:
Dihexa is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) system,it binds to HGF (Kd = 65 pM),and an analog of the peptide angiotensin IV.
CAS:
1401708-83-5
Formula:
C27H44N4O5
Molecular Weight:
504.672
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
CCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCCCCCC(N)=O
Target:
c-Met/HGFR

References

Mccoy A T , Benoist C C , Wright J W , et al. Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive/Antidementia Agents[J]. Journal of Pharmacology and Experimental Therapeutics, 2013, 344(1):141-154. Benoist C C , Kawas L H , Zhu M , et al. The Procognitive and Synaptogenic Effects of Angiotensin IV-Derived Peptides Are Dependent on Activation of the Hepatocyte Growth Factor/c-Met System[J]. Journal of Pharmacology and Experimental Therapeutics, 2014, 351(2):390-402.