TargetMol

PF-04979064

Product Code:
 
TAR-T7343
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7343-2mg2mg£95.00
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TAR-T7343-5mg5mg£111.00
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TAR-T7343-1mL1 mL * 10 mM (in DMSO)£116.00
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TAR-T7343-10mg10mg£142.00
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TAR-T7343-25mg25mg£214.00
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TAR-T7343-50mg50mg£287.00
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This product comes from: United States.
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Further Information

Bioactivity:
PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).
CAS:
1220699-06-8
Formula:
C24H26N6O3
Molecular Weight:
446.5
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
C[C@H](O)C(=O)N1CCC(CC1)n1c2c(cnc3ccc(nc23)-c2ccc(C)nc2)n(C)c1=O
Target:
PI3K; mTOR

References

Cheng H , Li C , Bailey S , et al. Discovery of the Highly Potent PI3K/mTOR Dual InhibitorPF-04979064 through Structure-Based Drug Design[J]. Med.chem.commun, 2013, 1(2):139-144.