TargetMol

SD 0006

Product Code:
 
TAR-T7276
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7276-1mg1mg£101.00
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TAR-T7276-2mg2mg£114.00
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TAR-T7276-5mg5mg£142.00
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TAR-T7276-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T7276-10mg10mg£182.00
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TAR-T7276-25mg25mg£270.00
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TAR-T7276-50mg50mg£389.00
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TAR-T7276-100mg100mg£546.00
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Further Information

Bioactivity:
SD 0006 is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.
CAS:
271576-80-8
Formula:
C20H20ClN5O2
Molecular Weight:
397.86
Pathway:
Autophagy; MAPK
Purity:
0.98
SMILES:
OCC(=O)N1CCC(CC1)c1n[nH]c(c1-c1ccncn1)-c1ccc(Cl)cc1
Target:
p38 MAPK; Autophagy

References

Walker J K , Selness S R , Devraj R V , et al. Identification of SD-0006, a potent diaryl pyrazole inhibitor of p38 MAP kinase[J]. Bioorganic & medicinal chemistry letters, 2010, 20(8):2634-2638.