TargetMol

Wilforine

Product Code:
 
TAR-T6S1049
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6S1049-1mg1mg£116.00
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TAR-T6S1049-5mg5mg£173.00
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TAR-T6S1049-10mg10mg£223.00
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TAR-T6S1049-1mL1 mL * 10 mM (in DMSO)£239.00
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TAR-T6S1049-25mg25mg£326.00
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TAR-T6S1049-50mg50mg£447.00
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TAR-T6S1049-100mg100mg£624.00
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Further Information

Bioactivity:
Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be mediated by down-regulation of the expression of inflammatory factors TNF-α, IL-6 and NO. It also has insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system.
CAS:
11088-09-8
Formula:
C43H49NO18
Molecular Weight:
867.854
Pathway:
Membrane transporter/Ion channel
Purity:
0.9867
SMILES:
C[C@H]1CCc2ncccc2C(=O)OC[C@]2(C)O[C@]34[C@H](OC(C)=O)[C@H]2[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@]3(COC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(=O)c2ccccc2)[C@H](OC1=O)[C@]4(C)O
Target:
ATPase

References

Miao GP, et al. Elicitation and in situ adsorption enhanced secondary metabolites production of Tripterygium wilfordii Hook. f. adventitious root fragment liquid cultures in shake flask and a modified bubble column bioreactor. Bioprocess Biosyst Eng. 2014 Zhu C, et al. Establishment of Tripterygium wilfordii Hook. f. Hairy root culture and optimization of its culture conditions for the production of triptolide and wilforine. J Microbiol Biotechnol. 2014 Jun 28;24(6):823-34.