TargetMol

Fraxinellone

Product Code:
 
TAR-T6S0071
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6S0071-5mg5mg£124.00
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TAR-T6S0071-1mL1 mL * 10 mM (in DMSO)£133.00
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TAR-T6S0071-10mg10mg£148.00
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TAR-T6S0071-25mg25mg£222.00
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TAR-T6S0071-50mg50mg£297.00
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TAR-T6S0071-100mg100mg£411.00
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Further Information

Bioactivity:
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding-deterrent activity, inhibition of growth, and larvicidal activity. 3. Fraxinellone has effect in the midgut metabolism of Mythimna separata (M. separata), via protease (especially the weak alkaline trypsin-like enzyme), carboxylesterase and glutathione S-transferase.
CAS:
28808-62-0
Formula:
C14H16O3
Molecular Weight:
232.279
Pathway:
Metabolism; Immunology/Inflammation; JAK/STAT signaling; Stem Cells; Chromatin/Epigenetic; Apoptosis; Cell Cycle/Checkpoint
Purity:
0.9935
SMILES:
CC1=C2C(=O)O[C@@H](c3ccoc3)[C@]2(C)CCC1
Target:
HIF/HIF Prolyl-Hydroxylase; STAT; PD-1/PD-L1

References

Sun Y , Qin Y , Gong F Y , et al. Selective triggering of apoptosis of concanavalin A-activated T cells by fraxinellone for the treatment of T-cell-dependent hepatitis in mice[J]. Biochemical Pharmacology, 2009, 77(11):1717-1724.