TargetMol

Pexmetinib

Product Code:
 
TAR-T6934
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6934-2mg2mg£114.00
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TAR-T6934-5mg5mg£149.00
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TAR-T6934-1mL1 mL * 10 mM (in DMSO)£168.00
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TAR-T6934-10mg10mg£197.00
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TAR-T6934-25mg25mg£324.00
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TAR-T6934-50mg50mg£503.00
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TAR-T6934-100mg100mg£550.00
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Further Information

Bioactivity:
Pexmetinib (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.
CAS:
945614-12-0
Formula:
C31H33FN6O3
Molecular Weight:
556.642
Pathway:
Autophagy; Tyrosine Kinase/Adaptors; MAPK
Purity:
0.9946
SMILES:
Cc1ccc(cc1)-n1nc(cc1NC(=O)NCc1cc(F)ccc1Oc1ccc2n(CCO)ncc2c1)C(C)(C)C
Target:
Tie-2; p38 MAPK; Autophagy

References

Koch K. 2013 AACR Annual Meeting.