TargetMol

Niraparib tosylate

Product Code:
 
TAR-T6892
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6892-2mg2mg£101.00
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TAR-T6892-5mg5mg£119.00
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TAR-T6892-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T6892-10mg10mg£139.00
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TAR-T6892-25mg25mg£166.00
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TAR-T6892-50mg50mg£191.00
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TAR-T6892-100mg100mg£266.00
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TAR-T6892-500mg500mg£547.00
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This product comes from: United States.
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Further Information

Bioactivity:
MK-4827(Niraparib) tosylate (with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
CAS:
1038915-73-9
Formula:
C26H28N4O4S
Molecular Weight:
492.59
Pathway:
Chromatin/Epigenetic; Apoptosis; DNA Damage/DNA Repair
Purity:
0.9987
SMILES:
Cc1ccc(cc1)S(O)(=O)=O.NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)[C@@H]1CCCNC1
Target:
Apoptosis; PARP

References

Mueller S, et al. Anticancer Res. 2013, 33(3):755-62. Patel AG, et al. J Biol Chem. 2012, 287(6):4198-210. Wang L, et al. Invest New Drugs. 2012, 30(6):2113-20. Bridges KA, et al. oncotarget. 2014, 5(13):5076-86. Jones P, et al. J Med Chem. 2009, 52(22):7170-85.