TargetMol

LTX315 acetate

Product Code:
 
TAR-T6881L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
 

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CodeSizePrice
TAR-T6881L-1mg1mg£125.00
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TAR-T6881L-2mg2mg£148.00
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TAR-T6881L-5mg5mg£182.00
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TAR-T6881L-10mg10mg£262.00
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TAR-T6881L-25mg25mg£446.00
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TAR-T6881L-50mg50mg£621.00
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Quantity:
TAR-T6881L-100mg100mg£854.00
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This product comes from: United States.
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Further Information

Bioactivity:
LTX315 acetate is an oncolytic peptide with potent anticancer activity, with IC50 values of 34.3 ?M for MRC-5, 8.3 ?M for A20, and 11 ?M for AT84, respectively.
CAS:
0
Formula:
C80H110N18O11
Molecular Weight:
1499.84
Purity:
0.9993
SMILES:
NCCCC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)C(c1ccccc1)c2ccccc2)=O)Cc(c[nH]3)c4c3cccc4)=O)CCCCN)=O)CCCCN)=O)Cc(c[nH]5)c6c5cccc6)=O)Cc(c[nH]7)c8c7cccc8)=O)CCCCN)=O)N.CC(O)=O

References

Haug BE, et al. Discovery of a 9-mer Cationic Peptide (LTX-315) as a Potential First in Class Oncolytic Peptide. J Med Chem. 2016 Apr 14;59(7):2918-27. Camilio KA, et al. Complete regression and systemic protective immune responses obtained in B16 melanomas after treatment with LTX-315. Cancer Immunol Immunother. 2014 Jun;63(6):601-13.