TargetMol

AS-604850

Product Code:
 
TAR-T6394
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6394-5mg5mg£102.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6394-1mL1 mL * 10 mM (in DMSO)£113.00
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Quantity:
TAR-T6394-10mg10mg£128.00
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Quantity:
TAR-T6394-25mg25mg£168.00
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Quantity:
TAR-T6394-50mg50mg£230.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6394-100mg100mg£367.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AS-604850 is a specific and ATP-competitive PI3Kγ inhibitor (IC50: 250 nM), 18-fold more selective for PI3Kγ than PI3Kα, and over 80-fold selectivity for PI3Kγ than PI3Kδ/β.
CAS:
648449-76-7
Formula:
C11H5F2NO4S
Molecular Weight:
285.22
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.9984
SMILES:
FC1(F)Oc2ccc(C=C3/SC(=O)NC3=O)cc2O1
Target:
PI3K

References

Hasan AM, et al, Int Immunopharmacol, 2010, 10(9), 12017-1021. Hohenester S, et al, J Hepatol, 2010, 53(5), 918-926. Camps M, et al, Nat Med, 2005, 11(9), 936-943. Lu C, Liu J, Escames G, et al.PIK3CG Regulates NLRP3/GSDMD-Mediated Pyroptosis in Septic Myocardial Injury.Inflammation.2023: 1-17.