TargetMol

(S)-crizotinib

Product Code:
 
TAR-T6357
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6357-2mg2mg£103.00
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TAR-T6357-5mg5mg£124.00
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TAR-T6357-1mL1 mL * 10 mM (in DMSO)£128.00
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TAR-T6357-10mg10mg£148.00
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TAR-T6357-25mg25mg£201.00
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TAR-T6357-50mg50mg£264.00
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TAR-T6357-100mg100mg£371.00
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Further Information

Bioactivity:
(S)-crizotinib?IC50 of 72 nM?, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.
CAS:
1374356-45-2
Formula:
C21H22Cl2FN5O
Molecular Weight:
450.34
Pathway:
DNA Damage/DNA Repair; Cell Cycle/Checkpoint; Apoptosis
Purity:
0.9989
SMILES:
C[C@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl
Target:
Apoptosis; DNA/RNA Synthesis; MTH1

References

Huber KV, et al. Nature. 2014 , 508(7495), 222-227.