TargetMol

RepSox

Product Code:
 
TAR-T6337
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6337-2mg2mg£103.00
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TAR-T6337-5mg5mg£119.00
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TAR-T6337-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T6337-10mg10mg£132.00
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TAR-T6337-25mg25mg£198.00
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TAR-T6337-50mg50mg£302.00
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Quantity:
TAR-T6337-100mg100mg£464.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
RepSox is a potent and selective of the TGFβR-1/ALK5 inhibitor.
CAS:
446859-33-2
Formula:
C17H13N5
Molecular Weight:
287.326
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; Stem Cells
Purity:
0.9857
SMILES:
Cc1cccc(n1)-c1n[nH]cc1-c1ccc2ncccc2n1
Target:
ALK; TGF-beta/Smad

References

Zhang S, Lou H, Lu H, et al.Characterization of Proliferation Medium and Its Effect on Differentiation of Muscle Satellite Cells from Larimichthys crocea in Cultured Fish Meat Production.Fishes.2023, 8(9): 429. Li J, Bai Y, Liu Y, et al.Transcriptome-based chemical screens identify CDK8 as a common barrier in multiple cell reprogramming systems.Cell Reports.2023, 42(6). Wang W, Ren S, Lu Y, et al. Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H2S production. The EMBO Journal. 2021 Jun 1;40(11):e106771. doi: 10.15252/embj.2020106771. Epub 2021 Apr 28. Gellibert F, et al. J Med Chem, 2004, 47(18), 4494-4506. Ichida JK, et al. Cell Stem Cell, 2009, 5(5), 491-503. Ma X, Lu Y, Zhou Z, Human expandable pancreatic progenitor?derived ? cells ameliorate diabetes. Science Advances. 2022, 8(8): eabk1826.