TargetMol

AZ191

Product Code:
 
TAR-T6257
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6257-2mg2mg£102.00
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TAR-T6257-5mg5mg£121.00
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TAR-T6257-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T6257-10mg10mg£143.00
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TAR-T6257-25mg25mg£206.00
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TAR-T6257-50mg50mg£287.00
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Further Information

Bioactivity:
AZ191?IC50 of 17 nM? is an effective and specific DYRK1B inhibitor. The specificity of AZ191 for DYRK1B is about 5- and 110-fold greater over DYRK1A and DYRK2, respectively.
CAS:
1594092-37-1
Formula:
C24H27N7O
Molecular Weight:
429.528
Pathway:
Tyrosine Kinase/Adaptors; Cell Cycle/Checkpoint
Purity:
0.9965
SMILES:
COc1cc(ccc1Nc1nccc(n1)-c1cn(C)c2cnccc12)N1CCN(C)CC1
Target:
DYRK

References

Wang C, Hu R, Wang T, et al.A bivalent ?-carboline derivative inhibits macropinocytosis-dependent entry of pseudorabies virus by targeting the kinase DYRK1A.Journal of Biological Chemistry.2023: 104605. Ashford AL, et al. Biochem J. 2014, 457(1), 43-56.