TargetMol

PF-04691502

Product Code:
 
TAR-T6251
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6251-1mg1mg£95.00
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TAR-T6251-2mg2mg£101.00
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TAR-T6251-5mg5mg£119.00
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TAR-T6251-1mL1 mL * 10 mM (in DMSO)£121.00
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TAR-T6251-10mg10mg£139.00
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TAR-T6251-25mg25mg£172.00
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TAR-T6251-50mg50mg£237.00
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TAR-T6251-100mg100mg£367.00
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This product comes from: United States.
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Further Information

Bioactivity:
PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.
CAS:
1013101-36-4
Formula:
C22H27N5O4
Molecular Weight:
425.489
Pathway:
Autophagy; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
Purity:
0.9863
SMILES:
COc1ccc(cn1)-c1cc2c(C)nc(N)nc2n([C@H]2CC[C@@H](CC2)OCCO)c1=O
Target:
Akt; PI3K; mTOR; Autophagy

References

Zhou Z, Cui D, Sun M H, et al. CAFs?derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling. The FASEB Journal. 2020 Simmons BH, Cancer Chemother Pharmacol, 2012, 70(2), 213-220 Zhou Z, Cui D, Sun M H, et al. CAFs?derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling[J]. The FASEB Journal. 2020. Kinross KM, Mol Cancer Ther, 2011, 10(8), 1440-1449 Yuan J, Mol Cancer Ther, 2011, 10(11), 2189-2199