TargetMol

Pyrroloquinoline quinone

Product Code:
 
TAR-T5692
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5692-100mg100mg£119.00
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Further Information

Bioactivity:
Pyrroloquinoline quinone (PQQ), as a well-known redox enzyme cofactor, PQQ can protect NS/PCs against glutamate toxicity associated with ROS-mediated mitochondrial pathway,
CAS:
72909-34-3
Formula:
C14H6N2O8
Molecular Weight:
330.208
Pathway:
Metabolism;
Purity:
0.98
SMILES:
OC(=O)c1cc2c([nH]1)-c1c(cc(nc1C(=O)C2=O)C(O)=O)C(O)=O
Target:
Endogenous Metabolite

References

Guan S , Xu J , Guo Y , et al. Pyrroloquinoline quinone against glutamate-induced neurotoxicity in cultured neural stem and progenitor cells[J]. International Journal of Developmental Neuroscience, 2015, 42:37-45. Saihara K, Kamikubo R, Ikemoto K,et al.Pyrroloquinoline Quinone, a Redox-Active o-Quinone, Stimulates Mitochondrial Biogenesis by Activating the SIRT1/PGC-1? Signaling Pathway[J].Biochemistry. 2017 Dec 19;56(50):6615-6625. Dongwei J , Fangfang D , Peike P , et al. Pyrroloquinoline-Quinone Suppresses Liver Fibrogenesis in Mice[J]. PLOS ONE, 2015, 10(3):e0121939-.