TargetMol

ABX-1431

Product Code:
 
TAR-T5353
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5353-2mg2mg£95.00
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Quantity:
TAR-T5353-1mL1 mL * 10 mM (in DMSO)£107.00
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Quantity:
TAR-T5353-5mg5mg£107.00
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TAR-T5353-10mg10mg£122.00
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TAR-T5353-25mg25mg£172.00
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TAR-T5353-50mg50mg£237.00
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Quantity:
TAR-T5353-100mg100mg£367.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ABX-1431 is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14 nM).
CAS:
1446817-84-0
Formula:
C20H22F9N3O2
Molecular Weight:
507.401
Pathway:
Metabolism
Purity:
0.998
SMILES:
FC(F)(F)C(OC(=O)N1CCN(Cc2ccc(cc2N2CCCC2)C(F)(F)F)CC1)C(F)(F)F
Target:
Lipase

References

Cisar JS, et al. Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders. J Med Chem. 2018 Oct 25;61(20):9062-9084.