TargetMol

4-IBP

Product Code:
 
TAR-T4596
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4596-2mg2mg£103.00
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TAR-T4596-1mL1 mL * 10 mM (in DMSO)£122.00
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TAR-T4596-5mg5mg£122.00
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TAR-T4596-10mg10mg£144.00
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TAR-T4596-25mg25mg£228.00
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TAR-T4596-50mg50mg£377.00
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Quantity:
TAR-T4596-100mg100mg£527.00
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Quantity:
TAR-T4596-200mg200mg£725.00
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This product comes from: United States.
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Further Information

Bioactivity:
4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .
CAS:
155798-08-6
Formula:
C19H21IN2O
Molecular Weight:
420.294
Pathway:
GPCR/G Protein
Purity:
0.9912
SMILES:
Ic1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)CC1
Target:
Sigma receptor

References

M?galizzi V, et al. 4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs. Neoplasia. 2