TargetMol

Pleconaril

Product Code:
 
TAR-T4536
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4536-1mg1mg£98.00
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TAR-T4536-2mg2mg£108.00
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TAR-T4536-1mL1 mL * 10 mM (in DMSO)£129.00
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TAR-T4536-5mg5mg£129.00
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TAR-T4536-10mg10mg£159.00
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TAR-T4536-25mg25mg£259.00
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TAR-T4536-50mg50mg£385.00
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TAR-T4536-100mg100mg£533.00
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Quantity:
TAR-T4536-200mg200mg£707.00
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This product comes from: United States.
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Further Information

Bioactivity:
Pleconaril is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM).
CAS:
153168-05-9
Formula:
C18H18F3N3O3
Molecular Weight:
381.355
Pathway:
Microbiology/Virology; Immunology/Inflammation
Purity:
0.9988
SMILES:
Cc1cc(CCCOc2c(C)cc(cc2C)-c2noc(n2)C(F)(F)F)on1
Target:
Virus Protease; Antiviral

References

Lacroix C, et al. In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses. Virol J. 2015 Jul 14;12:106. Benschop KS, et al. Genetic and antigenic structural characterization for resistance of echovirus 11 to pleconaril in an immunocompromised patient. J Gen Virol. 2015 Mar;96(Pt 3):571-9.