TargetMol

Linrodostat

Product Code:
 
TAR-T4532
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T4532-5mg5mg£112.00
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Quantity:
TAR-T4532-1mL1 mL * 10 mM (in DMSO)£117.00
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Quantity:
TAR-T4532-10mg10mg£134.00
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Quantity:
TAR-T4532-25mg25mg£201.00
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Quantity:
TAR-T4532-50mg50mg£289.00
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Quantity:
TAR-T4532-100mg100mg£422.00
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Quantity:
TAR-T4532-200mg200mg£589.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
CAS:
1923833-60-6
Formula:
C24H24ClFN2O
Molecular Weight:
410.92
Pathway:
Metabolism
Purity:
0.9984
SMILES:
C[C@H]([C@H]1CC[C@H](CC1)c1ccnc2ccc(F)cc12)C(=O)Nc1ccc(Cl)cc1
Target:
IDO; Indoleamine 2,3-Dioxygenase (IDO)

References

Lillian L. Siu, et al. Abstract CT116: BMS-986205, an optimized indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor, is well tolerated with potent pharmacodynamic (PD) activity, alone and in combination with nivolumab (nivo) in advanced cancers in a phase 1/2a trial. AACR; Cancer Res. 2017; 77 (13 Suppl): Abstract nr CT116.