TargetMol

HJC0152 hydrochloride

Product Code:
 
TAR-T4234
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4234-2mg2mg£106.00
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TAR-T4234-1mL1 mL * 10 mM (in DMSO)£121.00
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TAR-T4234-5mg5mg£121.00
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TAR-T4234-10mg10mg£145.00
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TAR-T4234-25mg25mg£224.00
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TAR-T4234-50mg50mg£328.00
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TAR-T4234-100mg100mg£530.00
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TAR-T4234-200mg200mg£551.00
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This product comes from: United States.
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Further Information

Bioactivity:
HJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor.
CAS:
1420290-99-8
Formula:
C15H14Cl3N3O4
Molecular Weight:
406.64
Pathway:
JAK/STAT signaling; Stem Cells; Apoptosis
Purity:
0.9862
SMILES:
Cl.NCCOc1ccc(Cl)cc1C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O
Target:
Apoptosis; STAT

References

Wang Y, et al. Suppression of the Growth and Invasion of Human Head and Neck Squamous Cell Carcinomas via Regulating STAT3 Signaling and the miR-21/?-catenin Axis with HJC20152. Mol Cancer Ther. 2017, 16(4):578-590. Chen C, Lu M, Lin S, et al. The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond?Blackfan anemia. Cell Death & Disease. 2020, 11(2): 1-11 Chen C, Lu M, Lin S, et al. The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond?Blackfan anemia[J]. Cell Death & Disease. 2020, 11(2): 1-11. Chen H, et al. Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents. ACS Med Chem Lett. 2013 Feb 14;4(2):180-185.