TargetMol

SAR-20347

Product Code:
 
TAR-T4210
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4210-1mg1mg£98.00
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TAR-T4210-2mg2mg£109.00
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TAR-T4210-5mg5mg£135.00
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TAR-T4210-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T4210-10mg10mg£189.00
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TAR-T4210-25mg25mg£329.00
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Quantity:
TAR-T4210-50mg50mg£535.00
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TAR-T4210-100mg100mg£740.00
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Quantity:
TAR-T4210-500mg500mg£1,428.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).
CAS:
1450881-55-6
Formula:
C21H18ClFN4O4
Molecular Weight:
444.85
Pathway:
JAK/STAT signaling; Chromatin/Epigenetic; Angiogenesis; Tyrosine Kinase/Adaptors; Stem Cells
Purity:
0.9954
SMILES:
NC(=O)c1nc(oc1Nc1ccc(cc1)C(=O)N1CCOCC1)-c1c(F)cccc1Cl
Target:
Tyrosine Kinases; JAK

References

Kang X, Yang M, Shi Y, et al. Interleukin-15 facilitates muscle regeneration through modulation of fibro/adipogenic progenitors. Cell Communication and Signaling. 2018 Jul 20;16(1):42 Works MG, et al. Inhibition of TYK2 and JAK1 ameliorates imiquimod-induced psoriasis-like dermatitis by inhibiting IL-22 and the IL-23/IL-17 axis. J Immunol. 2014 Oct 1;193(7):3278-87. Kang X, Yang M, Shi Y, et al. Interleukin-15 facilitates muscle regeneration through modulation of fibro/adipogenic progenitors[J]. Cell Communication and Signaling. 2018 Jul 20;16(1):42.