TargetMol

AG-494

Product Code:
 
TAR-T4205
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4205-5mg5mg£115.00
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Quantity:
TAR-T4205-1mL1 mL * 10 mM (in DMSO)£119.00
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Quantity:
TAR-T4205-10mg10mg£144.00
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Quantity:
TAR-T4205-25mg25mg£202.00
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Quantity:
TAR-T4205-50mg50mg£276.00
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Quantity:
TAR-T4205-100mg100mg£401.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
AG-494 is an inhibitor of epidermal growth factor receptor kinase.
CAS:
133550-35-3
Formula:
C16H12N2O3
Molecular Weight:
280.283
Pathway:
Cell Cycle/Checkpoint; Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Purity:
0.995
SMILES:
Oc1ccc(C=C(/C#N)C(=O)Nc2ccccc2)cc1O
Target:
EGFR; CDK

References

Sagara, Y. et al. Tyrphostins protect neuronal cells from oxidative stress. The Journal of Biological Chemisty 277(39), 36204-36215 (2002). Gazit, A. et al. Tyrphostins I: Synthesis and biological activity of protein tyrosine kinase inhibitors. Journal of Medicinal Chemistry 32(10), 2344-2352 (1989).