TargetMol

NBQX

Product Code:
 
TAR-T4113
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4113-1mg1mg£98.00
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TAR-T4113-5mg5mg£136.00
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TAR-T4113-1mL1 mL * 10 mM (in DMSO)£142.00
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TAR-T4113-10mg10mg£188.00
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TAR-T4113-25mg25mg£309.00
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TAR-T4113-50mg50mg£495.00
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TAR-T4113-100mg100mg£515.00
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TAR-T4113-200mg200mg£710.00
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This product comes from: United States.
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Further Information

Bioactivity:
Potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
CAS:
118876-58-7
Formula:
C12H8N4O6S
Molecular Weight:
336.28
Pathway:
Neuroscience; Membrane transporter/Ion channel
Purity:
0.9766
SMILES:
NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O
Target:
GluR; iGluR

References

Namba?et al?(1994) Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy. Brain Res.?638?36 Sheardown et al (1993) The pharmacology of AMPA receptors and their antagonists. Stroke 24 146 Zeman and Lodge (1992) Pharmacological characterization of non-NMDA subtypes of glutamate receptors in the neonatal rat hemisected spinal cord in vitro. Br.J.Pharmacol. 106 367 Gill et al (1992) The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline (NBQX) in a rat focal ischaemia model. Brain Res. 580 35