TargetMol

trans-ACPD

Product Code:
 
TAR-T3484
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3484-1mg1mg£103.00
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TAR-T3484-2mg2mg£116.00
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TAR-T3484-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T3484-5mg5mg£144.00
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TAR-T3484-10mg10mg£191.00
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TAR-T3484-25mg25mg£306.00
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TAR-T3484-50mg50mg£497.00
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TAR-T3484-100mg100mg£687.00
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Further Information

Bioactivity:
(?)-trans-ACPD is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD. (?)-trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate receptor); active at the group I/II mGlu receptors (EC50: 2/15/23/800 μM, mGluR2/1/5/4).
CAS:
67684-64-4
Formula:
C7H11NO4
Molecular Weight:
173.17
Pathway:
Neuroscience
Purity:
0.9953
SMILES:
[C@@]1(C[C@H](CC1)C(=O)O)(C(=O)O)N
Target:
GluR

References

Littman L, et al. Multiple mechanisms for inhibition of excitatory amino acid receptors coupled to phosphoinositide hydrolysis. J Neurochem. 1992 Nov;59(5):1893-904. Linden DJ, et al. Trans-ACPD, a metabotropic receptor agonist, produces calcium mobilization and an inward current in cultured cerebellar Purkinje neurons. J Neurophysiol. 1994 May;71(5):1992-8. C?rdova, M., Martins, D., Silva, M., Baggio, C., Carbonero, E., & Ruthes, A. et al. (2013). Polysaccharide glucomannan isolated from Heterodermia obscurata attenuates acute and chronic pain in mice.?Carbohydrate Polymers,?92(2), 2058-2064. doi: 10.1016/j.carbpol.2012.11.041