TargetMol

CHIR 98024

Product Code:
 
TAR-T3074
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3074-1mg1mg£100.00
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TAR-T3074-2mg2mg£111.00
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TAR-T3074-5mg5mg£148.00
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TAR-T3074-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T3074-10mg10mg£195.00
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TAR-T3074-25mg25mg£322.00
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TAR-T3074-50mg50mg£483.00
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TAR-T3074-100mg100mg£667.00
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Further Information

Bioactivity:
CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
CAS:
556813-39-9
Formula:
C20H17Cl2N9O2
Molecular Weight:
486.32
Pathway:
Stem Cells; MAPK; PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
Nc1nc(NCCNc2ncc(-c3ncc[nH]3)c(n2)-c2ccc(Cl)cc2Cl)ccc1[N+]([O-])=O
Target:
GSK-3; S6 Kinase

References

1. Ring DB,et al. Diabetes. 2003, 52(3), 588-595.