TargetMol

PD173955

Product Code:
 
TAR-T3063
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3063-1mg1mg£120.00
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TAR-T3063-2mg2mg£141.00
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TAR-T3063-5mg5mg£195.00
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TAR-T3063-1mL1 mL * 10 mM (in DMSO)£204.00
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TAR-T3063-10mg10mg£293.00
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TAR-T3063-25mg25mg£447.00
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TAR-T3063-50mg50mg£613.00
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TAR-T3063-100mg100mg£827.00
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This product comes from: United States.
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Further Information

Bioactivity:
PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and PKC.
CAS:
260415-63-2
Formula:
C21H16Cl2N4OS
Molecular Weight:
443.35
Pathway:
Apoptosis; Tyrosine Kinase/Adaptors; Cytoskeletal Signaling; Angiogenesis
Purity:
0.9928
SMILES:
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1
Target:
Apoptosis; Bcr-Abl; Src

References

1. Wisniewski D, et al. Cancer Res. 2002, 62(15), 4244-4255. 2. Moasser MM, et al. Cancer Res. 1999, 59(24), 6145-6152.