TargetMol

Decernotinib

Product Code:
 
TAR-T2636
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2636-1mg1mg£106.00
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TAR-T2636-2mg2mg£121.00
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TAR-T2636-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T2636-5mg5mg£148.00
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TAR-T2636-10mg10mg£179.00
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TAR-T2636-25mg25mg£291.00
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TAR-T2636-50mg50mg£463.00
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TAR-T2636-100mg100mg£643.00
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TAR-T2636-500mg500mg£1,259.00
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Further Information

Bioactivity:
Decernotinib(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.
CAS:
944842-54-0
Formula:
C18H19F3N6O
Molecular Weight:
392.38
Pathway:
Stem Cells; JAK/STAT signaling; Tyrosine Kinase/Adaptors; Chromatin/Epigenetic; Angiogenesis
Purity:
0.9964
SMILES:
CC[C@](C)(C(=O)NCC(F)(F)F)Nc1nc(ncc1)c1c[nH]c2c1cccn2
Target:
Tyrosine Kinases; JAK

References

1. Mahajan S, et al. J Pharmacol Exp Ther. 2015, 353(2), 405-414. 2. Farmer LJ, et al. J Med Chem. 2015, 58(18), 7195-7216.