TargetMol

OSI-930

Product Code:
 
TAR-T2624
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2624-1mg1mg£108.00
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TAR-T2624-2mg2mg£124.00
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TAR-T2624-1mL1 mL * 10 mM (in DMSO)£153.00
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TAR-T2624-5mg5mg£153.00
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TAR-T2624-10mg10mg£211.00
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TAR-T2624-25mg25mg£343.00
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TAR-T2624-50mg50mg£533.00
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TAR-T2624-100mg100mg£733.00
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Further Information

Bioactivity:
OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
CAS:
728033-96-3
Formula:
C22H16F3N3O2S
Molecular Weight:
443.44
Pathway:
MAPK; Tyrosine Kinase/Adaptors; Apoptosis; Angiogenesis
Purity:
0.9976
SMILES:
FC(F)(F)Oc1ccc(NC(=O)c2sccc2NCc2ccnc3ccccc23)cc1
Target:
Apoptosis; c-Fms; Raf; VEGFR; FLT; CSF-1R; Src; c-Kit

References

1. Garton AJ, et al. Cancer Res. 2006, 66(2):1015-1024. 2. Lin HL, et al. Drug Metab Dispos. 2011, 39(2), 345-350. 3. Han H W, Hahn S, Jeong H Y, et al. LINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent[J]. Scientific reports. 2018 Oct 8;8(1):14969.